Cognitive approaches conceptualizing face-name associative memory have demonstrated that associating unfamiliar faces with proper names is a task more complex than other visual memory tests because this is an arbitrary association. One of the endophenotypes proposed for Alzheimer’s disease (AD) is episodic memory tests. Our findings suggest FACEmemory® performance provides a useful gradation of impairment from normal aging to aMCI, and it is related to CSF AD biomarkers. ConclusionsįACEmemory® may be a promising memory prescreening tool for detecting subtle memory deficits related to AD. FACEmemory® scores and AD CSF biomarker levels were significantly correlated as well, mainly in the aMCI group. Automatically corrected FACEmemory® scores were highly correlated with the manually corrected ones. A cutoff of 31.5 in total FACEmemory® obtained 80.5% and 80.3% sensitivity and specificity values, respectively, for discriminating between CH and aMCI. Performance on FACEmemory® was progressively worse from CH to the naMCI and aMCI groups. A subsample of 65 individuals completed the S-FNAME, and 65 subjects received lumbar punctures. MethodsįACEmemory® was completed by 154 cognitively healthy (CH) individuals and 122 subjects with mild cognitive impairment, of whom 61 were non-amnestic (naMCI) and 61 amnestic (aMCI). The aims of the present study were (1) to determine whether FACEmemory® is a sensitive tool for the detection of cognitive impairment, (2) to examine whether performances on FACEmemory® are correlated with those on the S-FNAME (paper-and-pencil version with 16 images), and (3) to determine whether performances on FACEmemory® are related to AD biomarkers in the cerebrospinal fluid (CSF) (Aβ42, p-tau, and Aβ42/p-tau ratio). The test was minimally supervised by a psychologist to avoid technological problems during execution and scored manually to assess the reliability of the automatic scoring. The purpose of this study is to create the first self-administered episodic memory test, FACEmemory®, by adapting the FNAME-12 for tablet use with voice recognition, touchscreen answers, and automatic scoring. The current work advances this field by using voice recognition and touchscreen response format. The short form of the Face-Name Associative Memory Exam (FNAME-12), developed to detect preclinical and prodromal AD, asks individuals to learn the names and occupations associated with 12 faces. It implicates associative occipito-temporal cerebral regions, which are disrupted in AD. Memory for faces and proper names is a complex task because its association is arbitrary. The download links for the V4 downloads are still provided for those that prefer to work with the V4 bootable images.Computerized neuropsychological tests for early detection of Alzheimer’s disease (AD) have attracted increasing interest. In order to run MemTest86, PCs with legacy BIOS platform must use the older V4 release of MemTest86. However, you must use either Windows, Linux or Mac to create a bootable USB drive.įor information on creating a boot disk in Linux/Mac, visit the Technical Information pageĪs MemTest86 V10.4 supports only the newer UEFI platform, older PCs without UEFI support would be unable to boot MemTest86. The version of Windows, Linux, or Mac being used is irrelevant for execution. MemTest86 is a stand-alone program that does not require or use any operating system for execution.Installation and usage instructions are available on the Technical Information page.Please download the older V4 BIOS release of MemTest86 instead. On machines that don't support UEFI, MemTest86 will not boot. IMPORTANT: MemTest86 V10.4 images support only UEFI boot. * Once the purchase has been completed, a download link shall be provided that will contain the files needed to create your own bootable media.Ī pre-installed MemTest86 Pro USB Drive is available on our Pricing PageĪ site license is also available, for unlimited use of the software in a company, on our Pricing Page Documentation MemTest86 User Guide
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